4-Butylresorcinol strong inhibitory effect on tyrosinase activity raw material of cosmetics

DropBrigt ®4BR(4-butylresorcinol) has a strong inhibitory effect on tyrosinase activity. On the one hand, they can bind to the double copper ion of Tyrosinase, the active center of Tyrosinase, which is the Competitive inhibition of tyrosinase.

On the other hand, also has good antioxidant properties, and the first two stages of Melanin formation are one, the oxidation process. In the mechanism of whitening freckle, antioxidant and Competitive inhibition are the most common and the most important mechanism, and DropBright®4BR has both of these effects. In the three processes of Melanin source synthesis, DropBright®4BR not only has a very important inhibitory effect on tyrosinase activity, but also has a synergistic effect in whitening activity. DropBright ®4BR is a highly effective skin whitening brightener.

• Before Melanin Synthesis, it interferes with tyrosinase synthesis and glycosylation to prevent the enzyme from being absorbed by melanosomes.
• During Melanin Synthesis, inhibition of enzyme activity, which acts as a Competitive inhibition for tyrosinase and TRP1 enzymes, reduces the production of melanin-native by-products.
• After Melanin Synthesis, tyrosinase increased the degradation of melanocytes to inhibit the transfer of Keratinocytes, and because of the role of fatty acids photostripping effect. This function is enhanced by the presence of fatty acids and regulates tyrosinase degradation.