Azelaic acid with High fineness An oil-controlling acne-removing acid that inhibits 5α-reductase

DropCare^® AZE INCI Name is AZELAIC ACID. It is derived from the Latin Azelaic acidum and Azalea, that's why it's called Azalea acid. Dermatologists have discovered that the bacterium pityrosporum ovale, which causes pityriasis, causes a legacy of insufficient pigmentation.

It was later found in the culture of pityrosporum ovale that they oxidized oleic acid to azelaic acid.And then it is found that azelaic acid is an important skin whitening agent and a common drug for acne treatment.In 2003, our country used Azelaic acid as a medicinal component in medicine.

Laboratory and clinical trials have shown that azelaic acid is an effective tyrosinase inhibitor.It Can be used to treat some pigmentation diseases. Clinical application is effective and long-term use of patients can be well tolerated.15% and 20% Azelaic acid have been clinically proven to be effective for mild to moderate acne with few side effects.

The results of the bacteriostatic experiment showed that Azelaic acid had bacteriostatic effect on a variety of Gram-positive bacteria, with the lowest bacteriostatic concentration ranging from 0.4 to 1.6%.

Effect of azelaic acid on sebaceous glands - Dihydrotestosterone (DHT) -induced sebaceous gland activity is one of the causes of acne. 5α -reductase in sebaceous glands increases DHT conversion. The experiment of azelaic acid can compete effectively inhibit 5 alpha reductase and concentration dependent.

Effect of 20% Azelaic acid gel combined with placebo on acne severity index.